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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Circ Heart Fail. 2011 Jan 7;4(2):214–223. doi: 10.1161/CIRCHEARTFAILURE.110.958694

Figure 5. Knock-down of JPH2 increased store Ca2+ yet reduced RyR2-dependent caffeine-mediated store Ca2+ release.

Figure 5

A. Representative Ca2+ tracing of HL-1 cells following caffeine application. B. Bar graph showing mean amplitude of Ca2+ efflux from the SR in pCMS-shRNA-treated cells exposed to caffeine. Numbers in bar graph indicate number of cells analyzed. ***, P < 0.0001. C. Representative Ca2+ tracing of HL-1 cells following ionomycin treatment. D. Bar graph showing mean amplitude of Ca2+ efflux from all stores in pCMS-shRNA-treated cells exposed to ionomycin. Numbers in bar graph indicate number of cells analyzed. ***, P < 0.0001.

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