Table 1.

Comparison of mean sequence entropies of interface residues and noninterface residues for proteins known to be monomeric

Protein Data Bank code	Number of sequences*	Interface area†	〈s〉interface‡	〈s〉noninterface§	Ratio¶
1feh	25	1,575	0.98	0.78	1.26
1ako	18	845	1.05	0.90	1.16
1ton	642	704	1.17	1.07	1.09
1avp (1)	20	401	1.07	0.60	1.78
1avp (2)	20	383	0.88	0.60	1.47

^*The number of unique sequences may differ from that specified in the .hssp files because the latter includes redundancies. 

^† Buried solvent accessible surface area in the interface is measured in Ų. 

^‡ Mean sequence entropy calculated over interfacial residues (see Methods). 

^§ Mean sequence entropy calculated over all surface residues not involved in the interface. 

^¶ Ratio of interface to noninterface sequence entropy.