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Effects of MSCs treatment on diabetic polyneuropathy. Four weeks after intramuscular injection, MSCs settled in the gap between muscle fibers, through production of bFGF and VEGF, induces neovascularization and support regeneration of neural cells that results with improvement of diabetic polyneuropathy. Abbreviations: bFGF, basic fibroblast growth factor; MSC, mesenchymal stem cell; VEGF, vascular endothelial growth factor.
