Table 2.
Genes differentially regulated in sprouting neurons at day 7 in aged adult vs. young adult
| Chemokines/Cytokines |
| Mip1a/CCL3 |
| Mip1b/CCL4 |
| Mip2/CXCL2 |
| Interleukin 1 receptor antagonist |
| IL-27 |
| Bone morphogenic proteins |
| Growth differentiation factor 10 |
| ONECUT2 |
| Bone morphogenic protein 1 |
| Cytoskeletal proteins |
| Filamin A interacting protein |
| Supervillin |
| Actin related protein 2/3 complex, subunit 5-like |
| Actin-related protein 2 |
| Tyrosine ligase-like family member 7, transcript variant 2 |
| Cofilin 1 |
| Plastin 3 (down) |
| Calsyntenin (down) |
| Neurofilament heavy chain (down) |
| Alpha catenin (down) |
| Synaptogenesis Proteins |
| Piccolo |
| Synaptotagmin 1 |
| Synaptic vesicle glycoprotein 2b |
| Synaptophysin (down) |
| Protocadherin X |
| Adhesion molecules |
| Osteopontin |
| BEN/Alcam/CD166/Sc1 |
| Glypican 3 |
| CEA-related cell adhesion molecule 10 |
| Neurexin 1 |
| Cadherin 8 |
| Polyamine pathway |
| Spermidine/spermine N1-acetyl transferase |
| Arginase II (down) |
| Growth Factors |
| IGF-1 |
| Epidermal growth factor receptor (Egfr) |
| Glial cell line derived neurotrophic factor family receptor |
| alpha 3 |
| SORCS3 |
| Axonal Guidance |
| EphA4 |
| Lingo-1 |
| Kinases/Signaling Enzymes |
| PKCdeleta |
| Phospholipase C, gamma 2 (Plcg2) |
| Regucalcin (down) |
| Neuronal plasticity |
| Homer (down) |
| ARC (down) |
| Epigenetic or DNA modifying |
| ATRX |
| HDAC11 |
| Transcription Factors |
| Prrx1 |
| Lim Homeobox 9 |
| B cell translocation gene 1 |
| Janus kinase 1, Janus kinase 2 |
| Ring finger protein 29 (Rnf29) |
| Zinc finger protein 560 |
| E2F transcription factor 1 (E2f1) |
| General transcription factor IIa 2 (Gtf2a2) |
| Recombining binding protein suppressor of hairless |
| Egr1 (down) |
| Neuron-derived orphan receptor 1 (down) |
| Atf5 (down) |
| GTPases |
| Sec5l1 |
| Chimaerin 1 |
| Rho GDP dissociation inhibitor (GDI) alpha |
| Rho, GDP dissociation inhibitor (GDI) beta |
| Guanylate cyclase 1, soluble, alpha 3 |
| Mas1 oncogene (down) |
| Rab2b (down) |
| Immune Related |
| Toll-like receptor 2 |
| CD86 |
| Interferon gamma receptor 2 |
| MHC1RT1 class Ib_ locus S3 (RT1-S3) (down) |