Table 3.
Summary table of EPSP kinetic changes in response to tLTD paradigm (two action potential pairing).
Pyramidals (n = 3) | Non-pyramidal (n = 1) | |||
---|---|---|---|---|
Pre-pairing | Post-pairing | Pre-pairing | Post-pairing | |
Slope (mV/ms) | 2.22 ± 1.10 | 1.37 ± 1.06 (−38%) | 1.73 ± 0.51 | 1.05 ± 0.43 (−39%) |
Amplitude (mV) | 6.47 ± 2.89 | 3.64 ± 2.57 (−44%) | 6.76 ± 1.51 | 2.83 ± 1.05 (−58%) |
Half-width (ms) | 20 ± 2 | 12 ± 4 (−40%) | 30 ± 3 | 20 ± 7 (−33%) |
Decay time constant (ms) | 25 ± 3 | 15 ± 5 (−40%) | 34 ± 3 | 27 ± 11 (−20%) |
Onset (ms) | 1.76 ± 0.46 | 1.29 ± 0.38 (−27%) | 1.99 ± 0.09 | 1.63 ± 0.10 (18%) |
Input resistance (MΩ) | 41 ± 12 | 43 ± 13 (4%) | 155 ± 3 | 141 ± 7 (−9%) |
Data presented as mean ± S.E.M. and percent change between parenthesis. For non-pyramidal cell, data presented as mean ± S.D. and percent change between parenthesis.