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Excitatory action of GABA exerted on a P3 CA3 pyramidal cells. (A) Stimulation of MF in stratum lucidum (arrow) evoked in a P3 CA3 pyramidal cell (recorded in cell-attached) an action potential that was abolished by picrotoxin (100 μM). (B) GDPs recorded from a P3 CA3 pyramidal neuron (whole cell under current-clamp conditions) before (control) and after bath application of Isoguvacine (3 μM). Note the increase in GDPs frequency in isoguvacine.
