Skip to main content
. 2011 Mar 16;100(6):1517–1525. doi: 10.1016/j.bpj.2011.01.068

Figure 4.

Figure 4

DSC thermogram for the thermal denaturation of the c-MYC WT 24-mer G-quadruplex with 1:10 mols of TMPyP4/WT DNA in 30 mM [K+]. The raw excess heat capacity has been deconvoluted into three independent two-state processes. The lower melting conformer is attributed to the 1-6-1 isomer, and the higher melting conformer is attributed to the 1-2-1 isomer. The highest melting transition, which appears with the addition of TMPyP4, is for the melting of the TMPyP4 stabilized G-quadruplex complex.