A. Effect of fractions at different doses fraction 1(0, 18, 36,72μg/ml), fraction 2 and 3(0, 9,18, 36μg/ml, ) and fraction 4(0,18, 36,72μg/ml) of FAHF-2 on β-hexosaminidase released by RBL-2H3. B. Effect of fraction 2 on human skin mast cells. β-hexosaminidase release was triggered by mAb 22E7 or C5a. Data are mean±SD of 3 experiments. *p<0.05, **p<0.01,***p<0.001vs untreated control.