A. Down-regulation of Syk-phosphorylation (p-syk) in IgE-triggered RBL-2H3 cells by berberine, palmatine and jatrorrhizine combination (B+P+J). Bands are representative of three individual western blot experiments. B. Quantitative assay by densitometry of p-syk/β-actin ratio. All data are Mean ± SD of 3 individual experiments.*p<0.05, DNP+IgE+B+P+J vs DNP+IgE. C. Effects of B, P and J on IgE binding to RBL-2H3 cells. Red line=cells only without IgE, green=cells with IgE, purple, brown, blue= B, P, J +IgE.