Figure 8.
β1- and β3-integrin blockade diminished pressure-induced myogenic without affecting [Ca2+]i increases in response to pressure. (A) Percentage of [Ca2+]i change in arterioles exposed to an increase in intraluminal pressure before and after anti-β1-integrin. (B) Percentage of change in diameter before and after treatment with the inhibitory antibody (n = 6). (C) Percentage of [Ca2+]i change in arterioles exposed to an increase in intraluminal pressure before and after anti-β3-Integrin. (D) Percentage of change in diameter before and after treatment with the inhibitory antibody (n = 5). Data are presented as mean ± SEM.