Skip to main content
. Author manuscript; available in PMC: 2011 Mar 17.
Published in final edited form as: Gynecol Oncol. 2008 Apr 10;109(3):384–387. doi: 10.1016/j.ygyno.2007.11.046

Table 2.

Association between ovarian cancer risk and MLH1 nt-93, by age and family history

Subgroup Genotype Controls Cases OR a (95%CI) P-value
Age ≤ 50 GG 461 121 1
GA/AA 183/31 66/9 1.34 (0.96–1.86) 0.09
Age > 50 GG 461 283 1
GA/AA 183/31 173/28 1.53 (1.20–1.95) 0.0006
Family history
 negative
GG 461 316 1
GA/AA 183/31 188/28 1.47 (1.16–1.87) 0.001
Family history
 positive
GG 461 88 1
GA/AA 183/31 51/9 1.47 (1.02–2.12) 0.04
BRCA mutation GG 461 48 1
GA/AA 183/31 25/6 1.39 (0.86–2.25) 0.18
No BRCA
 mutation
GG 461 322 1
GA/AA 183/31 196/29 1.51 (1.19–1.90) 0.0007
a

All cases and controls in this table were from ethnic group “Other White”.