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. Author manuscript; available in PMC: 2011 Nov 11.
Published in final edited form as: J Med Chem. 2010 Nov 11;53(21):7599–7612. doi: 10.1021/jm1007209

Figure 1.

Figure 1

Fluorimetric calcium release traces from sea urchin egg homogenates induced by the addition of increasing concentrations of NAADP and three selected NAADP analogs. Calcium-ion concentration was measured fluorimetrically using the calcium sensitive dye Fluo-3. The effect of the addition of increasing concentrations of NAADP (1)(A), 5-NH2-NAADP (20)(B), 5-CH3-NAADP (21)(C), and 4-CH3-NAADP (17)(D) on fluorescence are shown.