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. Author manuscript; available in PMC: 2011 Nov 11.
Published in final edited form as: J Med Chem. 2010 Nov 11;53(21):7599–7612. doi: 10.1021/jm1007209

Table 2.

Result of the Pyridine Base Exchange Reaction

Structure R1 R2 # Name %Yield
graphic file with name nihms245301t4.jpg -NH2 -H 16 4-amino-NAADP 44
-CH3 -H 17 4-methyl-NAADP 43
-n-C4H9 -H 18 4-n-butyl-NAADP 60
-C6H5 -H 19 4-phenyl-NAADP 51
-H -NH2 20 5-amino-NAADP 43
-H -CH3 21 5-methyl-NAADP 59
-H -CO2H 22 5-carboxy-NAADP 32
-H -CH2CH3 23 5-ethyl-NAADP 59
-H -N3 24 5-azido-NAADP 61