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. 2011 Mar 2;12:33. doi: 10.1186/1471-2350-12-33

Table 2.

Characteristics of subjects according to SLC22A12 W258X genotype

Characteristics Males Females


WW WX XX P WW WX XX p
n = 3,256 n = 155 n = 2 n = 1,537 n = 70 n = 3
Age (years) 50.6 52.0 52.5 0.166 49.1 51.4 58.3 0.017
Body mass index (kg/m2) 23.5 23.7 20.9 0.240 22.0 21.9 19.7 0.407
Systolic blood pressure (mmHg) 121.0 120.5 105.0 0.319 114.4 115.1 119.3 0.811
Diastolic blood pressure (mmHg) 76.3 76.0 66.0 0.350 69.9 70.4 66.7 0.798
Total cholesterol (mg/dL) 202.3 202.7 195.5 0.944 207.2 208.9 197.3 0.793
HDL cholesterol (mg/dL) 57.7 56.0 63.5 0.338 71.1 69.7 88.3 0.159
Triglyceride (mg/dL) 124.7 129.0 66.0 0.460 85.1 85.2 73.3 0.895
AST (U/dL) 22.4 22.4 18.0 0.890 19.5 20.5 27.0 0.071
ALT (U/L) 25.5 26.6 18.5 0.732 17.1 19.5 24.7 0.066
GGT (U/L) 47.0 45.9 24.5 0.817 23.2 25.0 56.3 0.023
Creatinine (mg/dL) 0.86 0.82 0.90 0.001* 0.61 0.62 0.63 0.750
Blood urea nitrogen (mg/dL) 14.3 14.5 16.0 0.567 13.1 14.0 15.0 0.057
Blood glucose (mg/dL) 101.9 107.0 90.5 0.003* 93.7 95.2 89.7 0.434

HDL, high-density lipoprotein; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma-glutamyltransferase

p-value was calculated from one-way analysis of variance among WW, WX, and XX genotypes.

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