Table 2.
Dataset | Model | # SNPs | #Patients$ | Ratio Control/Case | FP [%] | FN [%] |
---|---|---|---|---|---|---|
1 | A | 500 | 300 | 2 | 5 | 5 |
2 | A | 1500 | 300 | 2 | 5 | 5 |
3 | A | 3000 | 300 | 2 | 5 | 5 |
4 | A | 500 | 600 | 2 | 5 | 5 |
5 | A | 1500 | 600 | 2 | 5 | 5 |
6 | A | 3000 | 600 | 2 | 5 | 5 |
7 | A | 500 | 300 | 2 | 10 | 10 |
8 | A | 1500 | 300 | 2 | 10 | 10 |
9 | A | 3000 | 300 | 2 | 10 | 10 |
10 | A | 500 | 600 | 2 | 10 | 10 |
11 | A | 1500 | 600 | 2 | 10 | 10 |
12 | A | 3000 | 600 | 2 | 10 | 10 |
13 | A | 500 | 300 | 2 | 20 | 20 |
14 | A | 1500 | 300 | 2 | 20 | 20 |
15 | A | 3000 | 300 | 2 | 20 | 20 |
16 | A | 500 | 600 | 2 | 20 | 20 |
17 | A | 1500 | 600 | 2 | 20 | 20 |
18 | A | 3000 | 600 | 2 | 20 | 20 |
19 | B | 500 | 150+150 | 2 | 5 | 5 |
20 | B | 1500 | 150+150 | 2 | 5 | 5 |
21 | B | 3000 | 150+150 | 2 | 5 | 5 |
22 | B | 500 | 300+300 | 2 | 5 | 5 |
23 | B | 1500 | 300+300 | 2 | 5 | 5 |
24 | B | 3000 | 300+300 | 2 | 5 | 5 |
25 | B | 500 | 150+150 | 2 | 10 | 10 |
26 | B | 1500 | 150+150 | 2 | 10 | 10 |
27 | B | 3000 | 150+150 | 2 | 10 | 10 |
28 | B | 500 | 300+300 | 2 | 10 | 10 |
29 | B | 1500 | 300+300 | 2 | 10 | 10 |
30 | B | 3000 | 300+300 | 2 | 10 | 10 |
31 | B | 500 | 150+150 | 2 | 20 | 20 |
32 | B | 1500 | 150+150 | 2 | 20 | 20 |
33 | B | 3000 | 150+150 | 2 | 20 | 20 |
34 | B | 500 | 300+300 | 2 | 20 | 20 |
35 | B | 1500 | 300+300 | 2 | 20 | 20 |
36 | B | 3000 | 300+300 | 2 | 20 | 20 |
37 | C | 500 | 300 | 2 | n.a. | n.a. |
38 | C | 1500 | 300 | 2 | n.a. | n.a. |
39 | C | 3000 | 300 | 2 | n.a. | n.a. |
40 | C | 500 | 600 | 2 | n.a. | n.a. |
41 | C | 1500 | 600 | 2 | n.a. | n.a. |
42 | C | 3000 | 600 | 2 | n.a. | n.a. |
$ For case rule A patients are equally distributed for the 4 case rules; for case rule B the first number indicates the number for rule 1, the second number for rule 2; n.a: not applicable.