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. 2011 Mar 17;7(3):e1001318. doi: 10.1371/journal.ppat.1001318

Figure 4. Antigen presentation by DCs is inhibited by opsonization.

Figure 4

Mice received 5×105 CFSE labeled SIINFEKL-specific cells one day prior to immunization i.d. with 5×104 P. berghei CS5M parasites in the right ear that had either been treated for 20 minutes with 100 µg/ml of either anti-P. knowlesi CS (2G3), anti-P. berghei CS (3D11) or F(ab′)2 fragments prepared from the 3D11 antibody. Three days later the mice were sacrificed and ear draining lymph nodes taken. A. Representative CFSE profiles of the SIINFEKL-specific population, values are the mean % of cells that had proliferated ± SEM in one of 4 similar experiments. B. The size of the expansion of the transferred SIINFEKL-specific cells (mean ± SEM n = 3; representative of 4 similar experiments).