Table 1:
Summary of laboratory investigations in a man with fever, cough and confusion shortly after a course of chemotherapy for Waldenström macroglobulinemia
| Investigation (normal range) | Result |
|---|---|
| Complete blood count | |
| Hemoglobin, g/L (140–180) | 93 |
| Leukocyte count, × 109/L (4.0–11.0) | 0.7 |
| Neutrophil count, × 109/L (2.0–7.5) | 0.2 |
| Lymphocyte count, × 109/L (1.5–4.0) | 0.1 |
| Platelet count, × 109/L (150–400) | 41 |
| Immunologic studies | |
| IgG level, g/L (7–16) | 2.6 |
| IgA level, mg/L (700–4000) | < 250 |
| IgM level, mg/L (400–2300) | 35 300 |
| CD4 count,* × 109/L (0.55–1.65) | 0.18 |
| Cerebrospinal fluid analysis | |
| Leukocyte count, × 106/L (0–5) | 4 |
| Glucose level, mmol/L (2.2–4.4) | 3.9 |
| Protein level, g/L (< 0.45) | 1.5 |
| Bacterial culture | Negative |
| Fungal culture | Negative |
| Cryptococcal antigen | Negative |
| Cytology | Lymphoma cells |
*
Performed two years before presentation.