Fig. 2.

The intestinal architecture of lkb1 mutants resembles that of starved WT larvae. (A, C, and E) High-power images depicting the liver and intestine of live larvae of the indicated genotypes; anterior is to the left. Red brackets demarcate the thickness of the intestinal wall, and livers are outlined. At 7 dpf, lkb1-mutant larvae (C) exhibit a small, dark liver (L) and flattened intestine (asterisk), as do starved 11-dpf WT larvae (E). (B, D, and F) H&E staining of sagittal sections of the intestine. Note loss of intestinal folding in 7-dpf lkb1- mutant larvae and in starved WT larvae. Sb, swim bladder.