Table 3.
Haplotypes* | All subjects | Low Risk | Intermediate or High Risk | P Value† | P value§ | |
---|---|---|---|---|---|---|
H1 | AAAGCT | 0.271 | 0.275 | 0.271 | 0.68 | 0.99 |
H2 | CAACCT | 0.196 | 0.185 | 0.200 | 0.18 | 0.67 |
H3 | CTAGGC | 0.189 | 0.195 | 0.190 | 0.64 | 0.98 |
H4 | CAAGCC | 0.186 | 0.188 | 0.181 | 0.52 | 0.96 |
H5 | CAAGCT | 0.089 | 0.102 | 0.083 | 0.01Ψ | 0.04 |
H6 | CAGGCT | 0.039 | 0.032 | 0.042 | 0.05 | 0.35 |
H7 | CAAGGC | 0.012 | 0.008 | 0.015 | 0.03 | 0.18 |
Overall | 0.04 |
The SNPs order is the same as given if Figure 1.
Two-sided chi-square test, each haplotype compared with all other haplotypes.
After 1000 permutation test.
OR for carriers versus non-carries, 0.80 (95% CI, 0.66–0.96).