Figure 1. Effect of L- and T-type blockers on myogenic tone of the basilar artery and branches.

A–C, pressure-induced myogenic tone was less in the main basilar artery (∼300 μm; A) than in small (∼103 μm; C) and large (∼200 μm; B) side branches. D–F, the contribution of L-type channels to myogenic tone decreased as vessel size decreased, while the contribution of T-type channels increased. Nifedipine (1 μmol L⁻¹) alone and in combination with mibefradil (1 μmol L⁻¹) was used to block L- and T-type channels, respectively. Data modified from Kuo et al. 2010.