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Ethanol administration delays degradation of iodinated cellular fibronectin in rats. Isolated hepatocytes were obtained from rats fed a control or ethanol-containing liquid diet for 4-6 wk. The degradation of iodinated cellular fibronectin (125I-cFn) that has been internalized by the hepatocytes was monitored over a 3-h time period as described in Material and Methods. Data are presented as femtomoles bound per μg DNA and are means ± SEM (n = 3 experiments).
