Table 3.
Incidence of histopathologic lesions (no. affected [%]) in right mandible and maxilla
WBN/KobSlc rats |
F344 rats |
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Male | Female | Male | Female | |
Caries | 47 (78.3%)ab | 7 (23.3%) | 3 (10.0%) | 0 |
Pulpitis | 39 (65.0%)ab | 6 (20.0%) | 1 (3.3%) | 0 |
Apical periodontitis | 32 (53.3%)ab | 5 (16.7%) | 1 (3.3%) | 0 |
Marginal periodontitis | 37 (61.7%)ab | 7 (23.3%) | 1 (3.3%) | 1 (3.3%) |
Gingivitis | 54 (90.0%)ab | 14 (46.7%) | 9 (30.0%) | 9 (30.0%) |
10 male WBN/KobSlc rats (60 molars) were evaluated; all other groups comprised 5 rats (30 molars)
Significant (P < 0.001) difference between male and female WBN/KobSlc rats
Significant (P < 0.001) difference male WBN/KobSlc and F344 rats