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Env is not required for viral uptake into target epithelial cells. (A) HIV Gag-iGFP transfer between Jurkat cells and HK-2 cells. (B) HIV Gag-iGFP/ΔCT in donor cells. (C) HIV Gag-iGFP ΔEnv, Env deficient virus, in donor cells. (D) HIV transfer normalized to HIV expression in donor cells is plotted for each of the mutants. Error bars represent SD from the mean of three independent experiments.
