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Pathologic markers of renal injury in TRPC6 WT and KO mice
| Kidney Damage | WT Mice (n = 11) | KO Mice (n = 10) | P |
|---|---|---|---|
| Mice with glomerular damage (sclerosis/collapse) | 72% | 40% | 0.13 |
| Mice with podocyte damage (desmin +) (with or without glomerular damage) | 82% | 50% | 0.12 |
| Mice with tubular microcysts (with or without glomerular or podocyte damage) | 92% | 60% | 0.10 |
