Table 1.
Response features of IID sensitive LSO units
| Kcna1+/+ | Kcna1−/− | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Parameter | Mean±s.e.m. | Median | 25% | 75% | n | Mean±s.e.m. | Median | 25% | 75% | n | Test | Significance |
| IID50 (dB) | 9.7 ± 2.4 | 7.3 | 3.9 | 19.7 | 25 | 13.6 ± 1.7 | 12.6 | 9.3 | 18.1 | 20 | MWRS-test | P= 0.278 |
| IIDdyn (dB) | 33 ± 2 | 35 | 29 | 40 | 25 | 40 ± 2 | 40 | 35 | 50 | 20 | t test | P= 0.017 |
| CFexc (kHz) | 19.4 ± 2.3 | 13.4 | 10.5 | 27.0 | 28 | 15.2 ± 1.4 | 12.6 | 9.1 | 23.0 | 31 | MWRS-test | P= 0.233 |
| CFinh (kHz) | 18.8 ± 2.4 | 16.2 | 10.5 | 23.2 | 18 | 19.6 ± 2.5 | 19.1 | 9.0 | 27.0 | 22 | MWRS-test | P= 0.989 |
| Q10 | 1.89 ± 0.22 | 1.54 | 1.08 | 2.61 | 28 | 1.49 ± 0.22 | 1.33 | 0.74 | 1.77 | 31 | MWRS-test | P= 0.103 |
| Spont. rate (spikes s−1) | 2.5 ± 1.1 | 0.4 | 0.0 | 1.8 | 28 | 3.6 ± 1.9 | 0.1 | 0.0 | 0.9 | 31 | MWRS-test | P= 0.344 |
| Max. rate (spikes s−1) | 168.1 ± 16.2 | 167.7 | 71.7 | 242.0 | 28 | 137.3 ± 18.5 | 128.0 | 46.3 | 212.5 | 31 | MWRS-test | P= 0.116 |
| Thresholdexc (dB SPL) | 47 ± 3 | 50 | 34 | 59 | 28 | 56 ± 3 | 60.0 | 47 | 66 | 31 | MWRS-test | P= 0.036 |
| Thresholdinh (dB SPL) | 43 ± 4 | 45 | 20 | 55 | 18 | 56 ± 3 | 58 | 45 | 70 | 22 | MWRS-test | P= 0.028 |
| Latency (ms) | 4.8 ± 0.5 | 4.0 | 3.7 | 4.6 | 25 | 5.2 ± 0.3 | 4.6 | 3.9 | 5.8 | 27 | MWRS-test | P= 0.056 |
| Jitter (ms) | 1.3 ± 0.7 | 0.3 | 0.1 | 0.6 | 25 | 1.1 ± 0.3 | 0.4 | 0.2 | 1.6 | 27 | MWRS-test | P= 0.079 |
| ISIonset (ms) | 3.55 ± 0.56 | 2.62 | 2.04 | 3.68 | 25 | 4.43 ± 0.59 | 3.18 | 1.81 | 6.71 | 27 | MWRS-test | P= 0.297 |