Table 3.
Transcripts changed >3-fold with treatment with cRA plus SAHA in the SKRC06 line
| Gene | Description | Fold change (cRA + SAHA/control) |
|---|---|---|
| dhrs9 | retinol-metabolizing enzyme | 7.9 |
| gata3 | GATA binding protein 3 | 4.4 |
| ceacam5 | Adhesion molecule | 4.1 |
| Il1 β | Interleukin 1 β | 4.0 |
| pcdh1 | Protocadherin family member | 3.4 |
| scap2 | Immune activation factor | 3.1 |
| phlda1 | Apoptotic marker carcinoma | 3.1 |
| artn | neurotophic factor | 3.0 |
| abcb1 | Multidrug transporter | 3.0 |
| Atf5 | Activating transcription factor 5 | 0.3 |
Genes with at least three fold higher mRNA levels in SKRC06 cells after treatment with a combination of both cRA (1 μM) and SAHA (0.5 μM). Genes are listed in order of fold-change. Gene descriptions are indicated.