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. 2010 Dec 6;50(4):735–739. doi: 10.1093/rheumatology/keq371

Table 1.

Univariable and multivariable associations between thumb pain, clinical assessments and the presence of ROA in the thumb (right hand)

Univariable OR (95% CI) Chi-square significance
Multivariable right thumba ROA
Outcome Frequency, % Right first CMC ROA Right thumba ROA βb P-valuec OR (95% CI)
Age group, years
    50–60 35.5 Reference 1.0 Reference 1.0
    60–70 37.3 1.6 (1.1, 2.5) 1.9 (1.3, 2.9) 0.6 0.005 1.8 (1.2, 2.6)
    ≤70 27.2 3.9 (2.5, 6.0) 5.4 (3.4, 8.6) 1.4 < 0.001 4.1 (2.5, 6.7)
P < 0.001 P < 0.001 Dropped
Gender 61.8 1.4 (1.0, 1.9) 1.5 (1.0, 2.0)
P = 0.077 P = 0.030
BMI
    <25 25.6 Reference 1.0
    25.0–29.9 43.8 0.7 (0.5, 1.1) 0.8 (0.6, 1.3) Dropped
    ≥30.0 30.6 0.8 (0.5, 1.3) 1.1 (0.7, 1.7)
P = 0.360 P = 0.354
Thumb pain during activity in the past month 53.2 2.1 (1.5, 2.9) 2.23 (1.6, 3.2) 0.6 0.001 1.8 (1.3, 2.6)
P < 0.001 P < 0.001
Thumb pain in the past month as indicated on a hand diagram 51.5 1.5 (1.0, 2.1) 1.4 (1.0, 2.0) Dropped
P = 0.018 P = 0.023
The presence of thenar muscle wasting 20.8 3.0 (2.0, 4.6) 3.1 (2.0, 5.0) 0.6 0.016 1.9 (1.1, 3.1)
P < 0.001 P < 0.001
The presence of nodes, deformity or enlargement 72.6 2.2 (1.5, 3.3) 3.1 (2.1, 4.5) 0.7 <0.001 2.1 (1.4, 3.1)
P < 0.001 P < 0.001
A positive grind test 12.2 1.8 (1.1, 2.9) 1.7 (1.0, 2.9) Dropped
P = 0.015 P = 0.027
A positive Finkelstein’s test 16.8 1.4 (0.9, 2.2) 1.2 (0.8, 1.9) Dropped
P = 0.092 P = 0.213
Inability to achieve position 10 of the Kapandji index 33.3 1.0 (0.7, 1.4) 1.0 (0.7, 1.4) Dropped
P = 0.511 P = 0.535
Thumb extension <40 degrees 55.3 1.3 (0.9, 1.8) 1.2 (0.8, 1.6) Dropped
P = 0.120 P = 0.413

aThumb ROA is defined as K&L grade ≥2 in any thumb joint (thumb IP, first MCP, first CMC and TS), bβ is parameter estimate, cP-value = significance level, missing data were <10.2%.