Table 2.
Treatment | Pulse number | Pulse height (ng/ml) | Pulse length (h) | Pulse area (ng/ml) | Interpulse interval (h) | Pulse frequency (no. pulses/h) |
---|---|---|---|---|---|---|
CONTROL-SAL | 9.2 ± 0.6 | 70.1 ± 5.7 | 0.62 ± 0.03 | 19.1 ± 1.4 | 1.23 ± 0.07 | 0.78 ± 0.06 |
ACTH -PULS | 7.7 ± 0.9 | 83.1 ± 13.5 | 0.53 ± 0.06 | 20.6 ± 4.8 | 1.46 ± 0.21 | 0.65 ± 0.07 |
Shown are mean ± sem of pulse height, interpulse interval, pulse frequency, pulse length, and pulse area analyzed using the PULSAR algorithm calculated from 12-h corticosterone profiles during the peak phase of corticosterone secretion (1500–0300 h) of control rats infused with saline (CONTROL-SAL) and rats treated with MP for 5 d and infused with pulsatile ACTH (4 ng/h, 5 min pulse, ACTH PULS) for 24 h.