N	ΔBW (g)	Δlean (g)	Δfat (g)	Food (g/24 h)	Activity (counts/24 h)	Hazard ratio vs placebo (95% CI)
Placebo	78	−53.7 ± 1.8	−39.8 ± 1.6	−12.4 ± 0.4	4.3 ± 0.5	29,509 ± 1,775	–
0.4 mg Imidapril	10	−30.0 ± 14.1***	−21.6 ± 10.5**	−8.9 ± 2.7*	7.9 ± 3.0	29,379 ± 7,205	1.23 (0.49–3.09)
1 mg Imidapril	14	−24.8 ± 6.9***	−13.4 ± 4.8***	−5.8 ± 1.8***	5.8 ± 3.4	21,170 ± 7,148	4.03*** (1.55–10.52)
10 mg Imidapril	15	−21.9 ± 6.8***	−14.9 ± 4.8***	−5.31.3***	6.3 ± 4.0	22,732 ± 9,073	6.35*** (2.37–17.01)
0.5 mg Bisoprolol	13	−37.8 ± 7.5**	−25.3 ± 5.7**	−9.3 ± 1.2**	5.8 ± 2.0	33,701 ± 6,559	1.35 (0.58–3.14)
2 mg Bisoprolol	14	−25.6 ± 13.2***	−20.4 ± 9.4***	−6.4 ± 3.0***	16.7 ± 6.9**	38,777 ± 6,981	0.54 (0.26–1.13)
5 mg Bisoprolol	23	−21.8 ± 10.6***	−16.7 ± 7.7***	−5.9 ± 1.9***	10.9 ± 2.0***	43,755 ± 3,741***	0.32*** (0.18–0.59)
50 mg Bisoprolol	20	−30.6 ± 9.8***	−24.4 ± 6.9***	−8.4 ± 1.6***	10.1 ± 2.0**	43,124 ± 5,722**	0.44* (0.23–0.83)
0.3 mg MT-102	14	−20.3 ± 14.6***	−9.7 ± 11.3***	−9.5 ± 2.4*	6.4 ± 2.9**	46,872 ± 6,684***	0.52**** (0.25–1.04)
3 mg MT-102	15	+17.8 ± 17.9***	+15.1 ± 13.8***	−4.3 ± 2.8***	12.9 ± 3.1***	51,268 ± 6,521***	0.29*** (0.15–0.57)