Figure 5.

Effects of learning on encoding of motif identity in CLM. a, Distributions of firing rates conditional on motif identity for rewarded (left), unrewarded (middle) and novel (right) motifs for the neuron shown in Figure 2a. Each row in each panel shows the firing rate distribution for a single motif. Motifs are arranged in order of ascending mean firing rates and the conditional probability is encoded in grayscale. The firing rates of this neuron allow greater disambiguation of motif identity for rewarded motifs than for novel motifs. b, Comparison of mean (±SEM) mutual information across all CLM neurons for rewarded, unrewarded, and novel motifs. Wilcoxon signed-rank test: *p < 0.01; **p < 10⁻⁵. c, Scatter plot illustrating distributions of information values for novel motifs and rewarded motifs. Each point represents a single neuron. Upper right, histogram of differences between mutual information values for rewarded vs novel motifs for all neurons. The arrow denotes the mean. d, Mean (±SEM) total entropy (squares) and noise entropy (circles) values over all CLM neurons. Paired t test: *p < 0.01; **p < 0.005.