Table 4.

Mediation analysis results between amygdala, habenula, and VTA/SN.

	Path a (X → M)	Path b (M → Y)	Path c′ (X → Y)	Mediation path a*b
MODEL 1 X (AMYGDALA)→Y (VTA/SN) MEDIATED BY M (HABENULA)
β	0.47	0.48	0.14	0.23
p-Values	0.0034*	0.0000*	0.0139	0.0002*
MODEL 2 X (HABENULA)→ Y (VTA/SN) MEDIATED BY) M (AMYGDALA)
β	0.51	0.14	0.48	0.07
p-Values	0.0003*	0.0153	0.0000*	0.0133

β denotes the regression coefficients and p-values are uncorrected. The mark “*” indicates significant connections at p < 0.05, Bonferroni corrected (p = 0.05/4 = 0.0125).