. Author manuscript; available in PMC: 2011 Oct 1.

Published in final edited form as: Hypertension. 2011 Feb 28;57(4):10.1161/HYPERTENSIONAHA.110.164350. doi: 10.1161/HYPERTENSIONAHA.110.164350

Table 2.

Parameters of oxidative stress

Parameters	Control SHR Liver	CRP transgenic SHR
Liver
SOD U/mg protein	0.363±0.038	0.297±0.014^‡
GSH-Px, μM GSH/min/mg protein	636±18	467±22^*
GR, μM NADPH/min/mg protein	115±14	142±14
CAT μM H₂O₂/min/mg protein	798±36	899±21^‡
GSH μM/mg protein	22.0±1.6	16.9±1.1^‡
TBARS nM/mg protein	0.829±0.045	1.328±0.086^*
CD nM/mg protein	19.5±1.1	24.2±2^‡
Renal cortex
SOD U/mg protein	0.386±0.019	0.304±0.022^‡
GSH-Px, μM GSH/min/mg protein	512±18	292±19^*
GR, μM NADPH/min/mg protein	236±23	268±19
CAT μM H₂O₂/min/mg protein	671±19	595±25^‡
GSH μM/mg protein	12.7±0.6	9.0±0.8^*
TBARS nM/mg protein	1.111±0.055	1.456±0.102^†
CD nM/mg protein	20.8±1.1	26.8±1.6^†

p<0.001,

^†

p<0.01,

^‡

p<0.05; SOD – superoxide dismutase; GSH-Px – seleno-dependent glutathione peroxidase; GR – glutathione reductase; CAT – catalase; GSH – glutathione; TBARS – thiobarbiturate acid reactive substances; CD – conjugated dienes