Figure 3.

Adoptive splenocyte transfer improves liver regeneration in T cell-deficient mice. Fifty million splenocytes (Spl) from WT or LTα^–/– mice were transferred to TCR mice 1 week prior to PH. Represents 1 of 2 independent experiments (5 mice per group). (A) ALT levels in serum at 48 hours after partial hepatectomy. (B) Increased DNA synthesis in T cell-deficient mice after transfer of splenocytes from WT but not from LTα-deficient mice. (C) Liver H&E sections at 48 hours after PH indicating the decreased injury in TCR mice reconstituted with WT but not LTα^–/– splenocytes. Original magnification, ×400.