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Schematic pathway of cell wall peptidoglycan metabolism adapted from Mengin-Lecreulx et al. [6]. Enzymes MurC, MurD and MurE are involved in de novo synthesis of the bacterial cell wall peptidoglycan. In Gram-negative bacteria, it is estimated that ∼30–60% of the peptidoglycan is recycled, and involves the enzyme Mpl.
