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. 2011 Mar 18;6(3):e17652. doi: 10.1371/journal.pone.0017652

Table 1. Allele frequencies and pairwise linkage disequilibrium coefficients for the SNPs harboured in the TNFSF4 gene.

Normalized linkage disequilibrium coefficient r2 (|D′|)
Polymorphism Minor allele frequencies rs1234315 rs10489266 rs45454293 rs3850641 rs10912564 rs1234313 rs10912558 rs3861950
rs1234315* 46.1/43.6
rs10489266 9.2/8.7 0.12 (1)
rs45454293 7.6/6.1 0.09 (1) 0.17 (1)
rs3850641* 15.4/12.0 0.19 (0.99) 0.22 (0.83) 0.70 (0.81)
rs10912564 32.4/32.6 0.001 (0.01) 0.05 (0.78) 0.02 (0.26) 0.04 (0.53)
rs1234313* 29.4/32.9 0.06 (0.86) 0.06 (0.93) 0.06 (0.91) 0.73 (0.93) 0.21 (0.98)
rs10912558 20.3/20.3 0.01 (0.21) 0.06 (0.80) 1 (1) 0.02 (0.28) 0.50 (0.98) 0.10 (0.94)
rs3861950* 33.4/30.1 0.003 (0.04) 0.06 (0.83) 0.02 (0.25) 0.04 (0.56) 0.89 (0.95) 0.20 (0.98) 0.47 (0.94)
rs1234312* 5.6/5.2 0.02 (0.31) 0.52 (1) 0.001 (0.01) 0.02 (0.31) 0.01 (1) 0.01 (1) 0.007 (1) 0.013 (1)

Results obtained in the combined male and female groups. *Polymorphisms that have been reported previously [5].

patients/controls. The two haplotype blocks identified across the gene are underlined and polymorphisms within each block having a high value for both D′ and r2 are indicated either in italics or bold, respectively.