Table 1. Allele frequencies and pairwise linkage disequilibrium coefficients for the SNPs harboured in the TNFSF4 gene.
Normalized linkage disequilibrium coefficient r2 (|D′|) | |||||||||
Polymorphism | Minor allele frequencies† | rs1234315 | rs10489266 | rs45454293 | rs3850641 | rs10912564 | rs1234313 | rs10912558 | rs3861950 |
rs1234315* | 46.1/43.6 | ||||||||
rs10489266 | 9.2/8.7 | 0.12 (1) | |||||||
rs45454293 | 7.6/6.1 | 0.09 (1) | 0.17 (1) | ||||||
rs3850641* | 15.4/12.0 | 0.19 (0.99) | 0.22 (0.83) | 0.70 (0.81) | |||||
rs10912564 | 32.4/32.6 | 0.001 (0.01) | 0.05 (0.78) | 0.02 (0.26) | 0.04 (0.53) | ||||
rs1234313* | 29.4/32.9 | 0.06 (0.86) | 0.06 (0.93) | 0.06 (0.91) | 0.73 (0.93) | 0.21 (0.98) | |||
rs10912558 | 20.3/20.3 | 0.01 (0.21) | 0.06 (0.80) | 1 (1) | 0.02 (0.28) | 0.50 (0.98) | 0.10 (0.94) | ||
rs3861950* | 33.4/30.1 | 0.003 (0.04) | 0.06 (0.83) | 0.02 (0.25) | 0.04 (0.56) | 0.89 (0.95) | 0.20 (0.98) | 0.47 (0.94) | |
rs1234312* | 5.6/5.2 | 0.02 (0.31) | 0.52 (1) | 0.001 (0.01) | 0.02 (0.31) | 0.01 (1) | 0.01 (1) | 0.007 (1) | 0.013 (1) |
Results obtained in the combined male and female groups. *Polymorphisms that have been reported previously [5].
patients/controls. The two haplotype blocks identified across the gene are underlined and polymorphisms within each block having a high value for both D′ and r2 are indicated either in italics or bold, respectively.