Skip to main content
. 2011 Mar 18;6(3):e17671. doi: 10.1371/journal.pone.0017671

Table 1. Eye abnormalities in αB-R120G knock-in mice.

Age (weeks) 3–8 12–20 40–56 Total (all ages combined)
Genotype Cataract (lens opacities)
Cataract stage Cataract stage Cataract stage
WT 2/10 (20%) 0–0.5(0.3±0.3) 1/4 (25%) 0–0.5(0.6±0.6) 4/7 (57%) 1–1.5(1.2±0.3) 7/21 (33%)
Het 17/17 (100%) 1–3(1.4±0.6) 6/10 (60%) 0.5–3(1.7±1.0) 10/10 (100%) 2–4(2.6±0.8) 31/37 (84%)
Homo 8/10 (80%) 0–2(1.2±0.9) 5/5 (100%) 2–4(2.6±0.9) 3/4 (75%) 3–4(3.2±1.2) 16/19 (84%)
Small eye and lens
WT 0/10 (0%) 0/4 (0%) 0/7 (0%) 0/21 (0%)
Het 5/17 (29%) 0/10 (0%) 3/10 (30%) 8/37 (22%)
Homo 2/10 (20%) 0/5 (0%) 2/4 (50%) 4/19 (21%)
Corneal abnormalities
WT 0/10 (0%) 0/4 (0%) 0/7 (0%) 0/21 (0%)
Het 2/17 (12%) 0/10 (0%) 0/10 (0%) 2/37 (5%)
Homo 1/10 (10%) 0/5 (0%) 2/4 (50%) 3/19 (16%)

WT, wild-type; Het, heterozygous; Homo, homozygous.