Table 5. Top differentially-affected pathwaysa.
| Pathway name | p-value |
| Immune response: TLR3 and TLR4 induce TICAM1 | 3.40×10−03 |
| Neurophysiological process: ACM regulation of nerve impulse | 2.59×10−03 |
| Development: EGFR signaling pathway | 1.47×10−09 |
| Immune response: CD28 signaling | 1.07×10−10 |
| Immune response: Regulation of T cell function by CTLA-4 | 1.18×10−08 |
| Immune response: CD40 signaling | 5.09×10−08 |
| Inhibitory action of Lipoxins and Resolvin E1 on neutrophil functions | 8.41×10−02 |
| Immune response: MIF-JAB1 signaling | 8.24×10−03 |
| Ca(2+)-dependent NF-AT signaling in Cardiac Hypertrophy | 2.02×10−02 |
| Muscle contraction: EDG5-mediated smooth muscle contraction | 2.03×10−02 |
a
Significance reflects absolute differences (by standard deviation) with respect to saline vs. LPS.