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. 2011 Mar 18;6(3):e17957. doi: 10.1371/journal.pone.0017957

Figure 1. In silico analysis of Notch pathway gene promoters.

Figure 1

In silico analysis of the genetic networks directly involved in Notch and Wnt signaling suggest overlap and direct crosstalk via Notch target gene activation through canonical Wnt signaling. By means of MatInspector, [33] gene promoters in the Notch pathway were found to contain at least one putative LEF-1/TCF-site (number of sites in per gene is described in square brackets). Genes in gray boxes were subjected for further semi quantitative RT-PCR analysis.