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. 2011 Mar 18;6(3):e18020. doi: 10.1371/journal.pone.0018020

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Meis et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Examples of GABAergic sIPSCs recorded in a LA projection neuron before and (B) during action of NPS. (C) Cumulative amplitude and (D) inter-event interval histograms obtained from the same neuron shown in (A, B) before addition of NPS and after a steady-state effect had been reached. (E) Normalized sIPSC amplitude and frequency pooled during control conditions and after addition of NPS exhibits a significant increase in sIPSC amplitude as well as frequency. (F) mIPSCs recorded in the presence of TTX were unchanged in amplitude as well as frequency by addition of NPS. * P<0.05, ** P<0.01.