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. 2011 Mar 18;6(3):e18020. doi: 10.1371/journal.pone.0018020

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Meis et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A, B) Examples of subthreshold oscillations in a LA projection neuron before (A) and during (B) action of NPS. (C) Corresponding FFT analysis illustrate predominant theta frequencies enhanced by NPS. (D) Peak amplitude as well as frequency are significantly enlarged by addition of NPS. (E, F) Examples of subthreshold oscillations in a LA projection neuron before (E) and during (F) action of NPS in the presence of AP-5 and DNQX to block glutamatergic transmission. (G) Corresponding FFT analysis illustrate block of NPS effect. (H) Peak amplitude as well as frequency are unchanged by NPS * P<0.05, ** P<0.01.