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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Exp Eye Res. 2011 Feb 12;92(4):251–259. doi: 10.1016/j.exer.2011.02.003

Figure 7.

Figure 7

Decreased expression of Cx46 with a reciprocal increase in Cx43 protein expression in Y79 tumors of mice treated with Cx46 siRNA. Conversely, tumors treated with a non-silencing siRNA or were untreated showed Cx46 upregulation and Cx43 downregulation. Equal amounts of Y79 tumor homogenate were analyzed for (A) Cx46 and (B) Cx43 where β-actin was used as the loading control. Lane 1: Tumor #14, sham treated tumor; Lane 2: Tumor #5, anti-Cx46 siRNA treated tumor; Lane 3: Tumor #11, AllStars negative control siRNA treated tumor; Lane 4: Y79 cell lysate positive control for Cx46 expression. Representative tumor western blots shown.