Figure 2. Activated NK cells ameliorate cholestatic liver injury.
Groups of 6 wild-type C57BL/6 mice were inoculated i.v. with 50 μl of saline, polyclonal rabbit anti-mouse asialo-GM1, or an equivalent concentration (37 mg/ml) of normal rabbit serum on day 2 prior to BDL. Plasma was collected from each group at 18 and 72 hours post-BDL, and the ALT levels were quantified. Data (means ± SD) are the combined results of 2 experiments (n=12). *Significantly greater than both other groups at comparable time points: P<0.05 (Kruskal-Wallis one way analysis of variance on ranks).