Table 1.
Descriptive characteristics of training sample: 41 ADNI subjects with PIB PET and CSF Aβ42 data.
| Characteristic | All (n = 41) |
CN (n = 9) |
aMCI (n = 22) |
AD (n = 10) |
|---|---|---|---|---|
| Female gender, no. (%) | 14 (34) | 4 (44) | 6 (27) | 4 (40) |
| Age, years, median (IQR) | 74 (71, 79) | 72 (71, 79) | 75 (73, 80) | 72 (70, 76) |
| APOE ε4 positive, no. (%) | 21 (51) | 2 (22) | 12 (55) | 7 (70) |
| Education, years, median (IQR) | 16 (12, 19) | 16 (12, 18) | 16 (14, 19) | 15 (12, 19) |
| MMSE, median (IQR) | 28 (25, 29) | 29 (28, 29) | 28 (26, 29) | 22 (21, 24) |
| CDR-SB, median (IQR) | 1.5 (0.9, 3.5) | 0.0 (0.0, 0.5) | 1.5 (1.0, 2.0) | 5.0 (4.1, 6.0) |
| PIB PET, median (IQR) | 2.1 (1.4, 2.3) | 1.4 (1.3, 1.7) | 2.3 (1.9, 2.4) | 2.1 (1.8, 2.4) |
| PIB Positive (>1.5 by PIB PET), no. (%) | 29 (71) | 3 (33) | 18 (82) | 8 (80) |
| PIBcalc, median (IQR) | 2.1 (1.6, 2.3) | 1.4 (1.4, 2.0) | 2.1 (1.8, 2.3) | 2.2 (2.0, 2.3) |
| PIB Positive (by PIBcalc), no. (%) | 32 (78) | 4 (44) | 19 (86) | 9 (90) |
Abbreviations: IQR, inter-quartile range; APOE, apolipoprotein E; MMSE, Mini-Mental State Examination; CDR-SB, Clinical Dementia Rating sum of boxes; PIB, Pittsburgh Compound B; PET, positron emission tomography; PIBcalc, calulated PIB PET based on CSF Aβ42.