Table 2.
Anthropometric and biochemical variables in the morbidly obese patients, classified according to their HOMA-IR, and the controls.
| Controls | MO-low-IR | MO-IR | |
|---|---|---|---|
| n (men/women) | 11 (3/8) | 22 (6/16) | 18 (6/12) |
| Age (years) | 49.2 ± 15.4 | 43.6 ± 13.4 | 41.0 ± 8.8 |
| Weight (kg) | 77.0 ± 13.0 | 145.2 ± 30.8a | 158.8 ± 24.8a |
| BMI (kg/m2) | 27.5 ± 2.1 | 54.5 ± 7.3a | 56.1 ± 5.9a |
| Waist (cm) | 84.8 ± 8.7 | 139.4 ± 20.6a | 150.6 ± 19.5a |
| Hip (cm) | 103.2 ± 7.4 | 154.9 ± 18.7a | 157.5 ± 13.1a |
| Waist-to-hip ratio | 0.88 ± 0.08 | 0.89 ± 0.06 | 0.95 ± 0.11 |
| Glucose (mmol/L) | 6.04 ± 0.60 | 5.47 ± 0.53 | 5.82 ± 0.65 |
| Cholesterol (mmol/L) | 4.87 ± 0.86 | 5.28 ± 1.08 | 4.86 ± 0.72 |
| Triglycerides (mmol/L) | 0.90 ± 0.41 | 1.28 ± 0.47 | 1.38 ± 0.85 |
| Free fatty acids (mmol/L) | 0.315 ± 0.030 | 0.739 ± 0.320a | 0.659 ± 0.234a |
| Insulin (pmol/L) | 76.7 ± 31.8 | 115.8 ± 28.2 | 280.9 ± 88.3a,b |
| HOMA-IR | 3.14 ± 1.43 | 3.90 ± 1.00 | 9.90 ± 2.90a,b |
| Aspartate aminotransferase (U/L) | 20.7 ± 8.3 | 20.1 ± 7.2 | 22.1 ± 7.6 |
| Alanine aminotransferase (U/L) | 42.2 ± 13.5 | 34.9 ± 12.0 | 48.2 ± 18.8b |
| γ-Glutamyltransferase (U/L) | 32.2 ± 17.0 | 54.5 ± 77.2 | 73.9 ± 110.0a |
| Leptin (ng/mL) | 10.0 ± 3.4 | 185.9 ± 97.6a | 189.7 ± 70.7a |
| Adiponectin (ng/mL) | 19.7 ± 8.27 | 11.0 ± 4.4a | 8.2 ± 4.17a,b |
The results are given as the mean ± SD. Comparison between the results of the three groups was made with one-way ANOVA, and the post hoc analysis was done with the Duncan multiple range test. Values were considered to be statistically significant when P ≤ 0.05.
a
Significant differences with the control group (P < 0.05).
b
Significant differences between the means of the 2 groups of morbidly obese patients (P < 0.05).