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. 2010 Dec 8;17(3-4):201–210. doi: 10.2119/molmed.2010.00197

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Copyright 2011, The Feinstein Institute for Medical Research

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Effects of rAAV1-SERCA2a transfer in regional myocardial perfusion. (A) ^99m Tc-MIBI SPECT images of control group. (B and C) ^99m Tc-MIBI SPECT images of the IHD+EGFP and the IHD+SERCA2a groups. The control group exhibited no detectable defect. At 4 wks after ameroid implantation, the two viral-administered groups exhibited a significant myocardial perfusion defect in the LAD coronary artery–dependent zone. No significant improvement of myocardial perfusion was detected at 8 wks after rAAV1-SERCA2a transfer in the IHD+SERCA2a group.