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Restoration of SERCA2a protein expression reverses the activation of ER stress–related apoptosis pathways. (A) The protein levels of CHOP, Bcl-2 and Bax. (B) The protein levels of procaspase 9, 12 (CASP9 and CASP12) and cleaved caspase 9, 12. (C) The protein levels of total and phospho-JNKs. Data are presented as mean ± SEM (n = 4~6 per group). *P < 0.05 versus control group; #P < 0.05 versus IHD+EGFP group.
