. Author manuscript; available in PMC: 2012 Apr 1.

Published in final edited form as: Calcif Tissue Int. 2011 Feb 15;88(4):272–280. doi: 10.1007/s00223-011-9473-5

Table 1.

In vitro generation of TRAP-positive multinucleated cells in bone marrow cell cultures from age-matched patients who were receiving alendronate (+AL) (n=5) and Control group (n=5).

	Control	+AL	p value, Control vs. +AL
Number of TRAP-Positive Multinucleated Cells/cm²
Basal Medium	547 ± 295	116 ± 99	p=0.015
M-CSF (25 ng/mL)	964 ± 403	381 ± 206	p=0.015
% effect M-CSF/Basal (p value, paired)	238 ± 174 (p=0.187)	576 ± 450 (p=0.062)
Alendronate (10⁻⁷ M)	236 ± 257
% effect Alendronate/Basal (p value, paired)	53 ± 58 (p=0.187)