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Interaction of CDR3 loops of MS2-3C8 with HLA-DR4. (A) Interactions between CDR3α and the α1 helix of HLA-DR4. (B) Interactions between CDR3β and the α1 and β1 helices of HLA-DR4. CDR3α, blue; CDR3β, orange; DR4 α chain, grey; DR4 β chain, yellow. Hydrogen bonds are shown as dotted red lines.
