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‘Biological’ ΔGXapp scales. (A) The mitochondrial ΔGappX scale derived from Leu/Ala-based H-segments with the indicated amino acid placed in the middle of the H-segment (see Supplementary Table S1). Averages from at least three independent experiments and standard errors are shown. (B) Comparison between the ΔGappX scales obtained for the mitochondrial inner membrane and for the mammalian ER membrane (Hessa et al, 2007).
