Table 1.

Clinical and demographic data of multiple sclerosis (MS) patients and healthy control subjects

Demographics	Relapsing-remitting MS	Secondary progressive MS	All MS	Controls
Subjects, no	17	3	20	20
Mean age, years (SD)	40.3 (13.9)	55.3 (9.3)	42.2 (13.3)	34.3 (11.0)
Sex male/female	5/12	2/1	7/13	10/10
Extended Disability Status Scale range/median/SD	0–4.5/3/1.3	4–6.5/6/1.3	0–6.5/3/1.7	/
Disease duration, years, range/mean/SD	1–35/11.2/10.2	11–36/23/12.5	1–36/13.1/11.1	/
Patients on medication, no	15/17	3/3	18/20	/
Patients on natalizumab, no/total	10/15	0	10/20	/
Relapses*, no, range/mean/SD	0–4/0.9/1.1	0	0–4/0.9/1.1	/
CSF positive†, no/total	16/17	3/3	19/20	/
MRI positive‡, no/total	17/17	3/3	20/20	/

^*In the previous 12 months.

^†Positive oligoclonal bands.

^‡Cerebral MRI indicative for MS according to Barkhof et al.¹⁴